If you liked
Kusuriya no Hitorigoto
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Raise wa Tanin ga Ii
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Both center a tough, pragmatic female lead who can hold her own, and shows little interest in the man romantically pursuing them. The male leads introduce problems the female lead has to contend with to push the plot forward. Each has dealt with a power imbalance in the relationship and the tension that it creates. Apothecary diaries is more of an external mystery focusing on medical and political cases, while yakuza fiancé is more of a psychological mystery focusing on understanding the characters– particularly Kirishima.